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About
Sponsors
Registration
Abstract Submission
Accommodations
Exhibitor Registration
Browse Exhibitors
Schedule of Events
Directions
Contact Information
36th Mid-Atlantic Macromolecular
Crystallography Meeting
June 1-3, 2006
Benson University Center
Wake Forest University, Winston-Salem, NC 27106
| Thursday, June 1 | |
| 1:30--3:30 PM | REGISTRATION & CHECK-IN Lobby, Level 3, Benson Center |
|
WELCOME AND OPENING REMARKSPugh Auditorium, Level 2
Dr. Al Claiborne, WFU Center for Structural Biology Dr. Michael Batalia, WFUHS Office of Technology Asset Management |
4:00--6:15 PM | KEYNOTE LECTURESPugh Auditorium, Level 2
Tomitake Tsukihara Professor, Laboratory of Protein Crystallography Institute for Protein Research Osaka University "Proton Pumping Mechanism of Cytochrome c Oxidase
Implicated by High Resolution X-ray Structures"
John E. (Jack) Johnson Professor, Department of Molecular Biology The Scripps Research Institute "Analysis of Virus Particle Maturation: Insights
into Elegantly Programmed Nano-machines"
|
| 6:30--7:00 PM | RECEPTIONMagnolia Room Lobby |
| 7:00-- | DINNERMagnolia Room |
| Friday, June 2 | |
| 8:15--9:00 AM | CONTINENTAL BREAKFASTRoom 410 (outside), Benson Center |
| 9:00--10:20 AM | Pugh Auditorium, Level 2
SESSION I
Chair: Matt Redinbo (Univ. of North Carolina) |
| 9:00--9:20 |
Matt Redinbo (Univ. of North Carolina)
Human Nuclear Receptors in Drug and Endobiotic Homeostasis |
| 9:20--9:40 |
Kevin Madauss (GlaxoSmithKline)
Structures of Progesterone Receptor Complexes with Asoprisnil and Corepressor Peptides Yield Insight into Steroid Receptor Modulation |
| 9:40--10:00 |
Charles Pemble (Wake Forest Univ.)
Thioesterase Domain of Human Fatty Acid Synthase: Structural Insights into Chain-Length Selectivity |
| 10:00--10:20 |
Stephen Soisson (Merck Research Labs)
Structural Basis for the Inhibition of Fatty Acid Synthesis by the Novel Antibiotic Platensimycin |
| 10:20--10:40 AM | COFFEE BREAKPugh Auditorium (outside) |
| 10:40 AM--12:40 PM | Pugh Auditorium, Level 2
SESSION II
Chair: Tom Hollis (Wake Forest Univ.) |
| 10:40--11:00 |
Tom Hollis (Wake Forest Univ.)
Structure and Substrate Specificity of the Dimeric 3'→5' Exonuclease, TREX1 |
| 11:00--11:20 |
Brandt Eichman (Vanderbilt Univ.)
Crystal Structure of 3-Methyladenine DNA Glycosylase I (Tag) in Complex with DNA |
| 11:20--11:40 |
Sandra Gabelli (Johns Hopkins Univ.)
Structure and Mechanism of the Farnesyl Diphosphate Synthase from Trypanosoma cruzi: Implications for Drug Design |
| 11:40--12:00 |
Joshua Warren (Duke Univ.)
The Structure of Human MutS-alpha: Phasing and Refining a Large Protein Assembly at Moderate Resolution |
| 12:00--12:20 |
Clara Kielkopf (Johns Hopkins Univ.)
Structural Basis of Polypyrimidine Tract Recognition by the Essential Pre-mRNA Splicing Factor, U2AF65 |
| 12:20--12:40 |
Miguel Garcia-Diaz (NIEHS)
DNA Scrunching During Gap-Filling by DNA Polymerase Lambda |
| 12:40--1:30 PM | LUNCH BREAKRoom 410 (outside), Benson Center |
| 1:30--3:00 PM | POSTER SESSION VENDOR SESSIONRoom 401, Benson Center |
| 2:00 PM | BUSINESS MEETINGPugh Auditorium, Level 2 |
| 3:00--4:00 PM | Pugh Auditorium, Level 2
SESSION III
Technology/Vendor Talks Chair: Conn Mallett (Rigaku Europe) |
| 3:00--3:20 |
Robert Collins (Wyatt Technology)
A Low Sample Volume, Automated Dynamic Light Scattering Technology for Protein Crystallization |
| 3:20--3:40 |
Zeeshan Farooq (Qiagen)
How a New Chemical Compatibility Test Facilitates Protein Crystallization |
| 3:40--4:00 |
Raza Shaikh (Formulatrix)
Formulatrix: Solutions for Automated Protein Crystallization |
| 4:00--4:20 PM | COFFEE BREAKPugh Auditorium (outside) |
| 4:20--5:20 PM | Pugh Auditorium, Level 2
SESSION IV
Chair: Bernie Brown (Wake Forest Univ.) |
| 4:20--4:40 |
Greg Buhrman (North Carolina State Univ.)
MSCS Analysis of the Ras-GppNHP Oncogenic Mutant Q61L |
| 4:40--5:00 |
Jiawei Wang (SAIC-Frederick)
Weak Anomalous Dispersion Data Collection at the Short Wavelength |
| 5:00--5:20 |
Zygmunt Derewenda (Univ. of Virginia)
NudEL - A Difficult (really) Structure |
| 5:30 PM | BUSES DEPART FOR DOWNTOWNBenson Center (outside) |
| 6:00--9:00 PM | DINNER4th Street Jazz & Blues |
| 8:00--10:00 PM | BUSES DEPART FROM DOWNTOWN |
| Saturday, June 3 | |
| 7:45--8:30 AM | CONTINENTAL BREAKFASTRoom 410 (outside), Benson Center |
| 8:30--10:10 AM | Pugh Auditorium, Level 2
SESSION V
Chair: Bob Kretsinger (Univ. of Virginia) |
| 8:30--8:50 |
Travis Gallagher (NIST)
Class IV Adenylyl Cyclase Reveals a Novel Fold |
| 8:50--9:10 |
Nathan Nicely (Wake Forest Univ.)
Structure of the Type III Pantothenate Kinase (CoaX) from Bacillus anthracis Refined at 2.0 Å Resolution: A Member of the ASKHA Superfamily |
| 9:10--9:30 |
Buvaneswari Narayanan (Univ. of Maryland)
Crystal Structure of PA4872 in Complex with Mg(II)/Oxalate |
| 9:30--9:50 |
Jamie Wallen (Wake Forest Univ.)
Structural Studies of Bacillus anthracis Coenzyme A-Disulfide Reductase in Complex with Pyridine Nucleotides |
| 9:50--10:10 |
Janusz Petkowski (Univ. of Virginia)
Crystal Structures of TM0549 and NE1324 - Two Orthologs of E. coli AHAS Isozyme III Small Regulatory Subunit |
| 10:10--10:30 AM | COFFEE BREAKPugh Auditorium (outside) |
| 10:30 AM--12:10 PM | Pugh Auditorium, Level 2
SESSION VI
Chair: Todd Lowther (Wake Forest Univ.) |
| 10:30--10:50 |
Thomas Jönsson (Wake Forest Univ.)
The Sulfinic Acid Switch in Peroxiredoxins: Structural Basis for the Reduction of Cysteine Sulfinic Acid by Sulfiredoxin |
| 10:50--11:10 |
Mike Eddins (Johns Hopkins Univ.)
Mms2/Ubc13 Covalently Bound to Ubiquitin: Structural Basis of Linkage-Specific Polyubiquitin Chain Formation |
| 11:10--11:30 |
David Shultis (Univ. of Virginia)
Structure of the Outer Membrane Cobalamin Transporter BtuB Complexed with TonB |
| 11:30--11:50 |
Michael Purdy (Univ. of Virginia)
Molecular Replacement with FAbs for Application to Integral Membrane Protein/Monoclonal Antibody FAb Complex Structure Determination |
| 11:50--12:10 |
Allison Williams (Duke Univ.)
Structure of UDP-N-acetylglucosamine Acetyltransferase with a Bound Antibacterial Pentadecapeptide |
| 12:10 PM | BOX LUNCH (take-out or eat-in) MEETING ADJOURNS Room 410 (outside), Benson Center |