Center for Structural Biology


Recent CSB Highlights:

  • Hollis and Perrino labs identify a redox regulatory mechanism for the HIV restriction factor, SAMHD1. link

  • Kim Nelson and Leslie Poole carry out an extensive functional and structural characterization of catalytic residues in a model decameric bacterial peroxiredoxin. link

  • Lowther and Howlett labs investigate the cannabinoid receptor interacting protein 1a competition with β-arrestin for CB1 receptor binding sites. link

The Center for Structural Biology at Wake Forest University (WFU) is an Interdisciplinary Organization which combines research and educational resources from WFU Health Sciences and WFU School of Medicine, the WFU Graduate School of Arts & Sciences, and the Undergraduate School of Arts & Sciences.  It is based at Wake Forest Biotech Place, 575 N. Patterson Avenue, Suite 550, Winston-Salem, North Carolina, 27101.

CSBWFU Faculty

Rebecca Alexander
Rebecca Alexander, PhD

Professor of Chemistry.

Larry Daniel
Larry Daniel, PhD

Professor of Biochemistry.

Patricia DosSantos
Patricia DosSantos, PhD

Associate Professor of Chemistry

Cristina Furdui
Cristina Furdui, PhD

Professor of Internal Medicine.

Tom Hollis
Tom Hollis, PhD

Professor of Biochemistry.

Todd Lowther
Todd Lowther, PhD

Professor of Biochemistry.

Doug Lyles
Doug Lyles, PhD

Professor and Chair of Biochemistry.

Jed Macosko
Jed Macosko, PhD

Associate Professor of Physics.

Kimberly Nelson
Kimberly Nelson, PhD

Assistant Professor of Biochemistry

Derek Parsonage
Derek Parsonage, PhD

Assistant Professor of Biochemistry.

Fred Perrino
Fred Perrino, PhD

Professor of Biochemistry.

Leslie Poole
Leslie Poole, PhD

Professor of Biochemistry and Director.

Fred Salsbury
Fred Salsbury, PhD

Associate Professor of Physics.

Emeritus Faculty

Al Claiborne
Al Claiborne, PhD

Professor of Biochemistry.

Roy Hantgan
Roy Hantgan, PhD

Associate Professor of Biochemistry.

Mark Lively
Mark Lively, PhD

Professor of Biochemistry.


Misty Allen
Center Coordinator
Telephone: 336 716-6775 336 716-6775

Chris Williamson, BS
Operations/Technical Support Analyst.
Telephone: 336 716-3149 336 716-3149

CSBWFU Facilities

Three hallmarks of the Center for Structural Biology at the Biotech Place include the X-Ray Diffraction Laboratory, the Biomolecular Computing and Graphics Facility, and the Biomolecular Resource Facility (BRF).

X-Ray Diffraction Laboratory
Biomolecular Computing and Graphics Facility
Macromolecular Interactions Core Laboratory (MICL)

Graduate Student Resources

Map and Directions

We are located Wake Forest Biotech Place, 575 N. Patterson Avenue, Suite 550, Winston-Salem, North Carolina 27101

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CSBWFU Contact Information

Leslie Poole</a>, Ph.D.
Leslie Poole, Ph.D.
Center for Structural Biology
336 716-6711 336 716-6711
Misty Allen
Misty Allen
Center Coordinator
Center for Structural Biology
336 716-6775 336 716-6775


Center for Structural Biology
Wake Forest University School of Medicine
Medical Center Boulevard
Winston-Salem, North Carolina 27157
FAX:  336 777-3242