WFULOGO

Center for Structural Biology

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Recent CSB Highlights:

  • The Hollis lab identifies inhibitors of the dNTP triphosphohydrolase SAMHD1 using a novel and direct high-throughput assay. link

  • Hollis and Perrino labs identify a redox regulatory mechanism for the HIV restriction factor, SAMHD1. link

  • Cristina Furdui and Leslie Poole develop mitochondria-targeted probes for imaging protein sulfenylation. link

  • Lowther lab identifies a novel hyperoxidation resistance motif in 2-Cys peroxiredoxins. link

The Center for Structural Biology at Wake Forest University (WFU) is an Interdisciplinary Organization which combines research and educational resources from WFU Health Sciences and WFU School of Medicine, the WFU Graduate School of Arts & Sciences, and the Undergraduate School of Arts & Sciences.  It is based at Wake Forest Biotech Place, 575 N. Patterson Avenue, Suite 550, Winston-Salem, North Carolina, 27101.

CSBWFU Faculty

Rebecca Alexander
Rebecca Alexander, PhD

Professor of Chemistry

Larry Daniel
Larry Daniel, PhD

Professor of Biochemistry

Patricia DosSantos
Patricia DosSantos, PhD

Associate Professor of Chemistry

Cristina Furdui
Cristina Furdui, PhD

Professor of Internal Medicine

Tom Hollis
Tom Hollis, PhD

Professor of Biochemistry and Co-Director of CSB

Todd Lowther
Todd Lowther, PhD

Professor of Biochemistry and Co-Director of CSB

Doug Lyles
Doug Lyles, PhD

Professor of Biochemistry

Jed Macosko
Jed Macosko, PhD

Associate Professor of Physics

Kimberly Nelson
Kimberly Nelson, PhD

Assistant Professor of Biochemistry

Derek Parsonage
Derek Parsonage, PhD

Assistant Professor of Biochemistry

Fred Perrino
Fred Perrino, PhD

Professor of Biochemistry

Leslie Poole
Leslie Poole, PhD

Professor of Biochemistry

Fred Salsbury
Fred Salsbury, PhD

Associate Professor of Physics

Emeritus Faculty

Al Claiborne
Al Claiborne, PhD

Professor of Biochemistry

Roy Hantgan
Roy Hantgan, PhD

Associate Professor of Biochemistry

Mark Lively
Mark Lively, PhD

Professor of Biochemistry

CSBWFU Staff

Misty Allen
Center Coordinator
Telephone: 336 716-6775 336 716-6775
mkallen@wakehealth.edu

Chris Williamson, BS
Operations/Technical Support Analyst
Telephone: 336 716-3149 336 716-3149
chris@csb.wfu.edu

CSBWFU Facilities

Three hallmarks of the Center for Structural Biology at the Biotech Place include the X-Ray Diffraction Laboratory, the Biomolecular Computing and Graphics Facility, and the Biomolecular Resource Facility (BRF).

X-Ray Diffraction Laboratory
Biomolecular Computing and Graphics Facility
Macromolecular Interactions Core Laboratory (MICL)

Graduate Student Resources

Map and Directions

We are located Wake Forest Biotech Place, 575 N. Patterson Avenue, Suite 550, Winston-Salem, North Carolina 27101


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CSBWFU Contact Information

Tom Hollis
Tom Hollis, PhD

Co-Director
Professor of Biochemistry

Todd Lowther
Todd Lowther, PhD

Co-Director
Professor of Biochemistry

Misty Allen
Misty Allen
Center Coordinator
Center for Structural Biology
336 716-6775 336 716-6775

Correspondence:

Center for Structural Biology
Wake Forest University School of Medicine
Medical Center Boulevard
Winston-Salem, North Carolina 27157
FAX:  336 777-3242